Food reference
Monash FODMAP Diet App
Serving-size data, recipes and reintroduction tools from the university team that developed the low-FODMAP diet. Priced in your app store.
Visit Monash →
Digital digestive care and IBS apps
Compare IBS apps and care programs
Nerva, Oshi, Cylinder, Ayble and Salvo side by side: what each includes, how care is delivered and how you get access. Plus the dedicated tools that do one job well.
Digestive care programs
Five programs at a glance.
Each program bundles care differently. Confirm what is included for you before you enroll.
| Compare | Nerva | Oshi Health | Cylinder | Ayble Health | Salvo Health |
|---|---|---|---|---|---|
| What it is | Personalized digital digestive care: clinical screening, gut-directed hypnotherapy, dietary guidance, symptom tracking and escalation when needed. | Virtual GI care with medical providers, registered dietitians and gut-brain specialists working as one team. | Digestive care combining a clinical team with diet and lifestyle support, courses and tracking tools. | Coordinated virtual digestive care with medical, nutrition and behavioral support in one plan. | Virtual gut-health clinic with a physician, registered dietitian and care navigator, for IBS and other GI conditions. |
| How care is delivered | In the Nerva app. Our clinical team screens and escalates when medical follow-up is needed; your existing clinicians manage diagnosis and complex care. | Virtual visits with GI, nutrition and gut-brain specialists. Check which services your plan includes. | Gastroenterologists, dietitians and health coaches. Check which services your program includes. | Clinician-led plan with diagnostics and prescribing, plus dietitians, pharmacists and coaches. | A diagnostic visit, then in-app messaging with your care team and a personalized care plan. |
| Your routine | A six-week core with guided sessions of around 15 minutes, then continued maintenance access. | A care plan built around scheduled virtual visits. | Care, dietary and lifestyle activities with courses, tracking and follow-up. | A coordinated plan with appointments and follow-up. | Daily symptom check-ins and ongoing messaging as a member. |
| Evidence | Randomized trial of the digital gut-directed hypnotherapy program in 244 adults with IBS. See the results | Published research. Check the population, comparator and outcomes in each study. | Published outcomes. Compare methods before drawing conclusions across programs. | Published research. Results are not interchangeable across programs. | No published outcomes on its site at the time of checking. |
| Getting access | Free assessment, then a subscription or referral price. Check access options | Insurance coverage, eligibility and out-of-pocket cost. | Employer or health-plan benefit. | Eligibility and the cost of the services in your plan. | Membership fee (FSA/HSA eligible) plus insurance for visits and tests; available in a limited set of US states. |
| Links | Explore Nerva → | Visit Oshi → | Visit Cylinder → | Visit Ayble → | Visit Salvo → |
Published by Mindset Health, the maker of Nerva. This is a guide to selected options, not an independent ranking, and no scores are assigned. Descriptions come from each program’s official site, checked September 7, 2026, and can change. The programs differ in scope; this comparison does not imply that one produces better outcomes than another.
Dedicated tools
Need help with one specific job?
A food reference, a barcode scanner or a symptom diary can each play a role alongside a care program.
Barcode scanner
Fig
Scan packaged foods to check them against low FODMAP and other dietary needs. Built with Monash-trained dietitians. Free to download.
Visit Fig →Barcode scanner
Spoonful
Scan a barcode for a traffic-light FODMAP result across elimination, reintroduction and personalization. Reviewed by Monash-trained dietitians.
Visit Spoonful →Food and symptom diary
mySymptoms
Log meals, symptoms and lifestyle factors, then export reports for your clinician. A pattern in a diary is a clue, not a diagnosis.
Visit mySymptoms →Free symptom diary
myIBS
A free IBS journal from the Canadian Digestive Health Foundation: symptoms, stool, food, sleep and stress, plus a Rome IV subtype questionnaire.
Visit myIBS →Tracker and program
Cara Care
Food and symptom tracking with FODMAP guidance. Its full prescription program is available in Germany through Bayer; the English app is a tracker.
Visit Cara Care →No longer available
Read about one of these? They are gone.
Older articles still list IBS apps that have since been acquired, withdrawn or shut down. Here is what happened to them, so you do not go looking.
Acquired · May 2025
Mahana IBS
What it was: An FDA-cleared prescription digital therapeutic delivering cognitive behavioral therapy for IBS.
What happened: Nerva acquired Mahana Therapeutics’ key assets and is incorporating its CBT content into the Nerva program. Former Mahana referrers can refer to Nerva.
Read the announcement →Removed · 2023
Zemedy
What it was: A CBT-based IBS care app from Bold Health.
What happened: Pulled from Google Play in 2023. Its website now redirects to an unrelated service.
Withdrawn from the US
Regulora
What it was: A prescription gut-directed hypnotherapy app from metaMe Health, FDA-cleared for abdominal pain in adults with IBS.
What happened: No longer being prescribed in the US as far as we can find, and its website now redirects to its maker’s corporate page. Nerva delivers gut-directed hypnotherapy without a prescription.
Status checked September 7, 2026. If you were using one of these, talk to your clinician about the options above.
Your personalized care program
Bring your digestive care together.
Nerva is a personalized digital digestive care program combining clinical screening, brain-gut behavioral care, dietary guidance, symptom tracking and escalation when needed. It includes a six-week core program and continued maintenance access.
- 01
Brain-gut behavioral care
Gut-directed hypnotherapy, CBT-informed education and practical exercises help you work on the gut-brain side of digestive care.
- 02
Dietary guidance
Bring dietary guidance into the same program as your behavioral care, with education to help you understand the dietary side of your symptoms.
- 03
Symptom tracking
Follow your symptoms through the six-week core program. Continued maintenance access lets you keep using your program and tools beyond the core.
- 04
Clinical screening and escalation
Our clinical team screens and escalates when medical follow-up is needed, while existing clinicians continue to manage diagnosis and complex care.
The Nerva difference
Clinical evidence behind Nerva.
Nerva’s digital gut-directed hypnotherapy program was evaluated in a randomized trial. Here is what it found.
81%1of participants met the primary symptom endpoint, compared with 63% on active control.
Randomized controlled trial · N=244 · active control · AJG 2025 Read the research →
- clinically significant abdominal-pain reduction, compared with 35% on control
- 71%
- adults randomized against a matched psychoeducation control
- 244
244 adults with IBS were randomized; 240 received the programs. The primary endpoint was a decrease of at least 50 points on the IBS Symptom Severity Scale at program completion. The trial evaluated a 42-session digital program with and without gut-directed hypnotherapy; its results apply to that studied intervention. Individual results vary.
Independent evaluation by PHTI
“Within the evidence reviewed, Nerva presented the strongest overall evidence for improving IBS symptoms.”
Peterson Health Technology InstituteVirtual Gastrointestinal Care Solutions, March 20262
Before you start
Your questions, answered.
Which IBS app or care program is best?
The one whose scope matches your needs and what you can access. Compare screening, behavioral and dietary care, medical services, follow-up and cost. Dedicated tools such as Monash and mySymptoms help with specific tasks.
Does Nerva include clinical care?
Nerva combines clinical screening, brain-gut behavioral care, dietary guidance, symptom tracking and escalation when needed. Our clinical team screens and escalates when medical follow-up is needed, while your existing clinicians manage diagnosis and complex care.
Can I use Nerva with the Monash FODMAP App?
Yes. Nerva includes dietary guidance as part of its program; the Monash app is a separate food reference. Discuss changes to an existing care plan with your clinician or dietitian. Explore low FODMAP and Nerva.
What does the research say about diet versus hypnotherapy?
A 2016 randomized study of 74 adults compared practitioner-delivered gut-directed hypnotherapy, a low-FODMAP diet and the two together. Symptoms improved in every group, with no detected difference between them. It did not test today’s Nerva program. Read Peters et al. (2016).
How should I compare costs?
Separate program enrollment, recurring subscriptions, prescription access and visit fees. Check trial expiry, renewal, cancellation, coverage and out-of-pocket charges before enrolling.
How much does Nerva cost, and how do I start?
The standard US offer is $199 USD for a 12-month subscription, with a 7-day free trial. A referral from a doctor or another healthcare practitioner brings the annual price to $149.25 USD. App-store offers may differ. Start with the free assessment and review your subscription terms before signing up. The Patient Assistance Program can help if cost is a barrier. You can also explore access options.
What happened to Mahana, Zemedy and Regulora?
Mahana Therapeutics was acquired by Nerva in May 2025 and its CBT content is being incorporated into the Nerva program. Zemedy was pulled from Google Play in 2023. Regulora is no longer being prescribed in the US as far as we can find. See the details.
What do Nerva members say?
Read member stories and review sources before you decide.
Get to know your Nerva care program.
Start with the free assessment and explore your personalized digestive care program. Review your access options before you begin.