For self-funded employers
Lower GI costs across your workforce.
Nerva uses AI to deliver personalized digestive care at workforce scale, without requiring a clinician for every employee. Employees get private, evidence-based care they can start immediately.
- 300,000+ people supported
- 8,000 active US providers
- RCT published in the AJG1
- Fees tied to agreed symptom outcomes
The workforce problem
Digestive health is already one of your largest workforce costs.
Digestive health does not appear as one neat claims category. It shows up across conditions, care settings and lost work, so the total cost is easy to underestimate.
- Conditions and symptoms
IBS, abdominal pain, bloating, constipation and diarrhea
- Medical claims
Primary care, gastroenterology, tests, medications and emergency care
- Workforce impact
Absence, disability and reduced productivity
Employer condition costs
Top 3
GI diseases are among employers' most costly condition groups.15
- reason adults visit the ED: stomach and abdominal pain.11
- #1
- of employed people with IBS report impairment while working.3
- 87%
The missing care layer
Most digestive care is built to find disease. Nerva supports people after the workup.
Existing providers should continue to diagnose disease and manage complex cases. Nerva gives employees with persistent abdominal pain, bloating, constipation or diarrhea a dedicated care path alongside that network.
Why claims repeat
- 1Persistent symptoms
- 2Repeat visits, tests and ED
- 3Clear structural work-up
Where Nerva intervenesTarget: lower claims and more productive time.
The solution
More digestive care without more appointments.
Nerva is a personalized digital digestive care program combining clinical screening, brain-gut behavioral care, dietary guidance, symptom tracking and escalation when needed. It includes a six-week core program and continued maintenance access.
- Multimodal gut-brain care
Care without an appointment
One 15-minute guided brain-gut session a day for six weeks: on their phone, wherever they are, with no appointment to book.
- AI-guided accountability
Daily support personalized by AI
AI adapts coaching, reminders, education and dietary guidance to each employee’s symptoms, preferences and goals.
- Outcomes and reporting
Validated symptom tracking
Employees see their progress through validated symptom check-ins. Employers receive aggregate outcome reporting.
- Clinical governance
Clinical support when needed
Our care team screens at intake, reaches out to members who go quiet, and escalates warning signs to a provider.
Clinical network
A provider network that brings members into care and supports the cases that need more.
Referring providers bring members into Nerva. Our clinical team screens and escalates when medical follow-up is needed, while existing clinicians continue to manage diagnosis and complex care.
- 8K+
- active US providers
- 50
- states
- 300K+
- people supported
Nerva platform data, August 2026.
The Nerva difference
The only virtual GI solution backed by a randomized controlled trial
Backed by 17 published studies, including a peer-reviewed randomized controlled trial.
81%1of participants met the primary symptom endpoint, compared with 63% on active control.
Randomized controlled trial · N=244 · active control · AJG 2025 Read the research →
- clinically significant abdominal-pain reduction, compared with 35% on control
- 71%
- lower six-month IBS management costs among Nerva completers.5
- 60%
RCT: n=244 randomized; n=240 primary analysis. Company-funded. Results do not imply cure or remission.
Independent evaluation by PHTI
“Within the evidence reviewed, Nerva presented the strongest overall evidence for improving IBS symptoms.”
Peterson Health Technology InstituteVirtual Gastrointestinal Care Solutions, March 20267
$1,889
Estimated annual net savings per commercial user7
Average annual net savings per user by category
- Functional GI$1,889
- MSK$1,300
- Depression / Anxiety$600
- Opioid Use / SUD$400
Member story
“My gut and my brain were stuck in a panic loop. A few weeks into Nerva, that signal shifted. I’m eating normally again, cooking with my family, going out without the dread.”
Size the GI savings opportunity in your own claims.
Our Accorded actuarial model identifies the persistent-symptom cohort, establishes today's cost and estimates enrollment, net savings and break-even.8
- expected gross ROI in Nerva's actuarial model, developed with Accorded.8
- 4.7x
10,000 covered employees
$43,000–$86,000Expected annual net savings8
$1,276net savings per enrolled member
Launch without a systems integration.
Use a company link or eligibility file. Add claims analysis to size the opportunity and set the baseline.
Per enrolled employee. Not PEPM.
Pay for employees who enroll, with fees tied to outcomes and optional claims evaluation.
- Eligibility list or company link
- Communications templates included
- Aggregate reporting on a cadence
- Optional claims analysis
Questions from self-funded employers
What does Nerva replace?
Nerva works alongside your carrier, TPA and medical network. It gives employees a scalable care pathway for persistent digestive symptoms while existing providers continue to manage diagnosis, structural disease and complex cases.
How do employees access Nerva?
Employees join privately through a company link or eligibility file and can begin immediately. No appointment or clinical-system integration is required.
What does the employer see?
Employers receive aggregate enrollment, engagement and outcomes reporting. Individual symptoms and progress remain private.
How is Nerva priced?
Nerva is priced per enrolled employee, not across the entire eligible population, with fees tied to agreed symptom outcomes.
How do we measure impact?
Start with a claims analysis to identify the cohort and establish the baseline. Then track validated symptom outcomes and claims impact using an evaluation method agreed before launch.
Find the GI savings opportunity in your workforce.
We'll identify the persistent-symptom cohort, establish the current cost baseline and size the implementation opportunity.
Fully insured? Bring your health plan into the conversation →
References
- Anderson, Ellen J.; Peters, Simone L.; Gibson, Peter R.; Halmos, Emma P. Comparison of Digitally Delivered Gut-Directed Hypnotherapy Program With an Active Control for Irritable Bowel Syndrome. The American Journal of Gastroenterology 120(2):p 440-448, February 2025. DOI: 10.14309/ajg.0000000000002921
- Frändemark, Å. et al. Work Productivity and Activity Impairment in Irritable Bowel Syndrome (IBS): A Multifaceted Problem. The American Journal of Gastroenterology, 2018;113(10):1540–1549: 86.8% of employed IBS patients reported impairment while at work and 24.4% reported missed work due to IBS.
- Peters, S. L.; Gibson, P. R.; Halmos, E. P. App-delivered gut-directed hypnotherapy halves the long-term costs associated with managing Irritable Bowel Syndrome (IBS) symptoms and improves work productivity. Retrospective study of 17,000+ Nerva users, presented at Digestive Disease Week: IBS management costs fell from USD 1,259 to USD 502 over six months, with significant long-term improvements in work absenteeism, presenteeism and overall productivity. Retrospective completer analysis, not a controlled trial.
- Lacy, B. E. et al. ACG Clinical Guideline: Management of Irritable Bowel Syndrome. The American Journal of Gastroenterology, 2021.
- Peterson Health Technology Institute. Virtual Gastrointestinal Care Solutions Assessment. March 2026. PHTI estimated $1,889 in average annual net savings per commercial user for wraparound functional GI care, using IBS as the representative condition. Cross-assessment estimates were $1,300 for MSK, $600 for depression and anxiety, $400 for opioid use and substance use disorder, with no savings identified for hypertension or diabetes.
- Nerva actuarial model developed with Accorded, August 2026: expected economics net of the model's expected per-enrollee fee. The range uses 6.75% to 13.5% enrollment across a 10% addressable, 50% eligible and reachable population.
- Centers for Disease Control and Prevention, National Hospital Ambulatory Medical Care Survey: stomach and abdominal pain is the most common principal reason for adult emergency department visits. See also Wu et al., Academic Emergency Medicine, 2025, on ED abdominal-pain presentations 2007–2019.
- Mindset Health participation in the CMS ACCESS Model, 2026: outcomes-based arrangements in the musculoskeletal and behavioral health tracks. ACCESS coverage does not extend to GI.
- Springbuk. Employee Health Trends 2025: gastrointestinal diseases are among the three most costly condition groups for employers.